› 1g1i

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN FROM ROTAVIRUS NSP4

Released:
DOI: 10.2210/pdb1g1i/pdb
PDB entry 1g1i coloured by chain, front view.
PDB entry 1g1i coloured by chain, side view.
PDB entry 1g1i coloured by chain, top view.
Source organism: Simian rotavirus A/SA11
Primary publication:
Crystal structure of the oligomerization domain of NSP4 from rotavirus reveals a core metal-binding site.
Bowman GD, Nodelman IM, Levy O, Lin SL, Tian P, Zamb TJ, Udem SA, Venkataraghavan B, Schutt CE
J Mol Biol 304 861-71 (2000)
PMID: 11124032

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137888 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural glycoprotein 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 43 amino acids
Theoretical weight: 5.4 KDa
Source organism: Simian rotavirus A/SA11
Expression system: Not provided
UniProt:
  • Canonical: P04512 (Residues: 95-137; Coverage: 25%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21212
Unit cell:
a: 35.47Å b: 35.399Å c: 60.937Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.235 0.245
Expression system: Not provided

Quick links

Citations

12 review citations

Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes.
Uversky VN. (2011)
11 more

4 mentions without citation

Epitope mapping and use of epitope-specific antisera to characterize the VP5* binding site in rotavirus SA11 NSP4.
Hyser et al. (2008)
3 more