› 1g04

Solution NMR

SOLUTION STRUCTURE OF SYNTHETIC 26-MER PEPTIDE CONTAINING 145-169 SHEEP PRION PROTEIN SEGMENT AND C-TERMINAL CYSTEINE

Released:
DOI: 10.2210/pdb1g04/pdb
PDB entry 1g04 coloured by chain, ensemble of 21 models, front view.
PDB entry 1g04 coloured by chain, ensemble of 21 models, side view.
PDB entry 1g04 coloured by chain, ensemble of 21 models, top view.
Source organism: Ovis aries
Primary publication:
Sheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solution.
Kozin SA, Bertho G, Mazur AK, Rabesona H, Girault JP, Haertlé T, Takahashi M, Debey P, Hoa GH
J Biol Chem 276 46364-70 (2001)
PMID: 11577109

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150109 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 26 amino acids
Theoretical weight: 3.43 KDa
Source organism: Ovis aries
Expression system: Not provided
UniProt:
  • Canonical: P23907 (Residues: 145-169; Coverage: 11%)
Gene names: PRNP, PRP, SIP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing torsion angle dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

Polyproline-II helix in proteins: structure and function.
Adzhubei et al. (2013)
20 other articles

4 mentions without citation

The Human Antibody Response to the Influenza Virus Neuraminidase Following Infection or Vaccination.
Rajendran et al. (2021)
3 more