1fyt Summary details

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spacer CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1
Summary
Header IMMUNE SYSTEMsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.6 Å, R-factor: 22.1%, Free R-factor: 25.5%, Spacegroup: C 1 2 1
Released 08/11/2000, deposition: 03/10/2000, last revision: 13/07/2011
Authors Hennecke, J.search; Carfi, A.search; Wiley, D.C.search
Primary citation Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1.
EMBO J.search vol:19, pag:5611-5624 (2000) [PubMed 11060013 ]search
Keywords protein-protein complexsearch, immunoglobulin foldsearch, IMMUNE SYSTEMsearch
Organism Homo sapiens(human) 9606search(A B D E),H3N2 subtype 119210search(C)
UniProt P01903search (A)
P04229search (B)
P03437search (C)
P01848search (D)
P01850search (E)
Solvent A, B, C, D, E
Related entries 1dlh
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN Protein P01903 (DRA_HUMAN)search
181 99%
B HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN Protein P04229 (2B11_HUMAN)search
192 93%
C HEMAGGLUTININ HA1 PEPTIDE CHAIN Protein P03437 (HEMA_I68A0)search
13 100%
D T-CELL RECEPTOR ALPHA CHAIN Protein P01848 (TCA_HUMAN)search
212 93%
E T-CELL RECEPTOR BETA CHAIN Protein P01850 (TRBC1_HUMAN)search
245 97%
Heterogens
Chain Id Name Ligands
A SUGAR (N-ACETYL-D-GLUCOSAMINE) NAG search
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