Assemblies
Multimeric state:
hetero pentamer
Accessible surface area:
36284.77 Å2
Buried surface area:
14215.64 Å2
Dissociation area:
1,228.36
Å2
Dissociation energy (ΔGdiss):
-0.57
kcal/mol
Dissociation entropy (TΔSdiss):
13.9
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134724
Macromolecules
Chain: A
Length: 181 amino acids
Theoretical weight: 21.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Pfam:
InterPro:
SCOP:
Length: 181 amino acids
Theoretical weight: 21.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P01903 (Residues: 26-206; Coverage: 79%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- MHC class II, alpha chain, N-terminal
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
SCOP:
Chain: B
Length: 192 amino acids
Theoretical weight: 22.32 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Pfam:
InterPro:
SCOP:
Length: 192 amino acids
Theoretical weight: 22.32 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P01911 (Residues: 30-221; Coverage: 81%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- MHC class II, beta chain, N-terminal
SCOP:
Chain: C
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: H3N2 subtype
Expression system: Escherichia coli
UniProt:
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: H3N2 subtype
Expression system: Escherichia coli
UniProt:
- Canonical: P03437 (Residues: 322-334; Coverage: 2%)
Chain: D
Length: 212 amino acids
Theoretical weight: 23.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Domain of unknown function (DUF1968)
InterPro:
SCOP:
Length: 212 amino acids
Theoretical weight: 23.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01848 (Residues: 1-97; Coverage: 69%)
Pfam: Domain of unknown function (DUF1968)
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin subtype
- Immunoglobulin V-set domain
- T-cell receptor alpha chain, constant domain
SCOP:
Chain: E
Length: 245 amino acids
Theoretical weight: 27.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Immunoglobulin C1-set domain
InterPro:
SCOP:
Length: 245 amino acids
Theoretical weight: 27.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01850 (Residues: 1-133; Coverage: 76%)
Pfam: Immunoglobulin C1-set domain
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin subtype
- Immunoglobulin V-set domain
SCOP: