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KLEBSIELLA AEROGENES UREASE, NATIVE

X-ray diffraction
2.2Å resolution
PDB entry 1fwj coloured by chain, front view.
PDB entry 1fwj coloured by chain, side view.
PDB entry 1fwj coloured by chain, top view.
Source organism: Klebsiella aerogenes
Assembly composition:
hetero nonamer (preferred)
Entry contents: 3 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero nonamer
Accessible surface area: 55344.93 Å2
Buried surface area: 48184.43 Å2
Dissociation area: 9,328.33 Å2
Dissociation energy (ΔGdiss): 127.12 kcal/mol
Dissociation entropy (TΔSdiss): 38.31 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-148349

Macromolecules

Urease subunit gamma
Chain: A
Length: 100 amino acids
Theoretical weight: 11.1 KDa
Source organism: Klebsiella aerogenes
Expression system: Klebsiella aerogenes
UniProt:
  • Canonical: P18316 (Residues: 1-100; Coverage: 100%)
Gene name: ureA
Pfam: Urease, gamma subunit
InterPro:
CATH: Urease, gamma-like subunit
SCOP: Urease, gamma-subunit
Urease subunit gamma in PDB entry 1fwj, assembly 1, front view.
Urease subunit gamma in PDB entry 1fwj, assembly 1, side view.
Urease subunit gamma in PDB entry 1fwj, assembly 1, top view.
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Urease subunit beta
Chain: B
Length: 106 amino acids
Theoretical weight: 11.71 KDa
Source organism: Klebsiella aerogenes
Expression system: Klebsiella aerogenes
UniProt:
  • Canonical: P18315 (Residues: 1-106; Coverage: 100%)
Gene name: ureB
Pfam: Urease beta subunit
InterPro:
CATH: Urease, beta subunit
SCOP: Urease, beta-subunit
Urease subunit beta in PDB entry 1fwj, assembly 1, front view.
Urease subunit beta in PDB entry 1fwj, assembly 1, side view.
Urease subunit beta in PDB entry 1fwj, assembly 1, top view.
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Urease subunit alpha
Chain: C
Length: 567 amino acids
Theoretical weight: 60.41 KDa
Source organism: Klebsiella aerogenes
Expression system: Klebsiella aerogenes
UniProt:
  • Canonical: P18314 (Residues: 1-567; Coverage: 100%)
Gene name: ureC
Pfam:
InterPro:
CATH:
SCOP:
Urease subunit alpha in PDB entry 1fwj, assembly 1, front view.
Urease subunit alpha in PDB entry 1fwj, assembly 1, side view.
Urease subunit alpha in PDB entry 1fwj, assembly 1, top view.
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