1fva Summary

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CRYSTAL STRUCTURE OF BOVINE METHIONINE SULFOXIDE REDUCTASE

The structure was published by Lowther, W.T., Brot, N., Weissbach, H., and Matthews, B.W., in 2000 in a paper entitled "Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PEPTIDE METHIONINE SULFOXIDE REDUCTASE.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PEPTIDE METHIONINE SULFOXIDE REDUCTASE P54149 (13-229) (MSRA_BOVIN)search Bos taurussearch 93% 217 92%
B PEPTIDE METHIONINE SULFOXIDE REDUCTASE P54149 (13-229) (MSRA_BOVIN)search Bos taurussearch 93% 217 92%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P54149 (13 - 229) PEPTIDE METHIONINE SULFOXIDE REDUCTASE Bos taurus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P54149) Peptide methionine sulfoxide reductasesearch Peptide Methionine Sulfoxide Reductase; Chain Asearch PF01625: Peptide methionine sulfoxide reductasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P54149) peptide-methionine (S)-S-oxide reductase activitysearch oxidoreductase activitysearch oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptorsearch oxidation-reduction processsearch protein repairsearch response to oxidative stresssearch mitochondrionsearch extracellular vesicular exosomesearch cytoplasmsearch

Chain InterPro annotation
A, B Peptide methionine sulphoxide reductase MsrAsearch Peptide methionine sulfoxide reductasesearch