1fub Summary

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FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA

The structure was published by Von Dreele, R.B., Stephens, P.W., Smith, G.D., and Blessing, R.H., in 2000 in a paper entitled "The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding." (abstract).

This crystal structure was determined using Powder diffraction and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely INSULIN, A CHAIN and INSULIN, B CHAIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INSULIN, A CHAIN P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
C INSULIN, A CHAIN P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
B INSULIN, B CHAIN P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%
D INSULIN, B CHAIN P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01308 (90 - 110) INSULIN, A CHAIN

Chain Structural classification (SCOP) Sequence family (Pfam)
A, C (P01308) Insulin-likesearch PF00049: Insulin/IGF/Relaxin familysearch
B, D (P01308) Insulin-likesearch PF00049: Insulin/IGF/Relaxin familysearch
Chain InterPro annotation
A, C Insulin-likesearch Insulin, conserved sitesearch
B, D Insulinsearch Insulin-likesearch