1fq0 Summary

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KDPG ALDOLASE FROM ESCHERICHIA COLI

The structure was published by Wymer, N., Buchanan, L.V., Henderson, D., et al., Fierke, C.A., Toone, E.J., and Naismith, J.H., in 2001 in a paper entitled "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of KDPG ALDOLASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A KDPG ALDOLASE P0A955 (1-213) (ALKH_ECOLI)search Escherichia coli K-12search 100% 213 100%
B KDPG ALDOLASE P0A955 (1-213) (ALKH_ECOLI)search Escherichia coli K-12search 100% 213 100%
C KDPG ALDOLASE P0A955 (1-213) (ALKH_ECOLI)search Escherichia coli K-12search 100% 213 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A955 (1 - 213) KDPG ALDOLASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C (P0A955) Class I aldolasesearch Aldolase class Isearch PF01081: KDPG and KHG aldolasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C (P0A955) catalytic activitysearch lyase activitysearch 2-dehydro-3-deoxy-phosphogluconate aldolase activitysearch identical protein bindingsearch 4-hydroxy-2-oxoglutarate aldolase activitysearch metabolic processsearch cytoplasmsearch cytosolsearch membranesearch

Chain InterPro annotation
A, B, C KDPG/KHG aldolasesearch Aldolase-type TIM barrelsearch