1fps Summary



The structure was published by Tarshis, L.C., Yan, M., Poulter, C.D., and Sacchettini, J.C., in 1994 in a paper entitled "Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of FARNESYL DIPHOSPHATE SYNTHASE. This molecule has the UniProt identifier P08836 (FPPS_CHICK)search. The sample contained 348 residues which is 95% of the natural sequence. Out of 348 residues 348 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A FARNESYL DIPHOSPHATE SYNTHASE P08836 (20-367) (FPPS_CHICK)search Gallus gallussearch 95% 348 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08836 (20 - 367) FARNESYL DIPHOSPHATE SYNTHASE Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P08836) Isoprenyl diphosphate synthasessearch Farnesyl Diphosphate Synthasesearch PF00348: Polyprenyl synthetasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P08836) metal ion bindingsearch dimethylallyltranstransferase activitysearch geranyltranstransferase activitysearch transferase activitysearch steroid biosynthetic processsearch sterol biosynthetic processsearch geranyl diphosphate biosynthetic processsearch isoprenoid biosynthetic processsearch cholesterol biosynthetic processsearch steroid metabolic processsearch cholesterol metabolic processsearch farnesyl diphosphate biosynthetic processsearch lipid metabolic processsearch cytoplasmsearch

Chain InterPro annotation
A Polyprenyl synthetasesearch Terpenoid synthasesearch