› 1fps

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF RECOMBINANT FARNESYL DIPHOSPHATE SYNTHASE AT 2.6 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1fps/pdb
PDB entry 1fps coloured by chain, front view.
PDB entry 1fps coloured by chain, side view.
PDB entry 1fps coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution.
Tarshis LC, Yan M, Poulter CD, Sacchettini JC
Biochemistry 33 10871-7 (1994)
PMID: 8086404

Function and Biology Details

Reactions catalysed: 
Prenyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140391 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl pyrophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 40.02 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P08836 (Residues: 20-367; Coverage: 95%)
Gene name: FDPS
Sequence domains: Polyprenyl synthetase
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I4122
Unit cell:
a: 88.6Å b: 88.6Å c: 276.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.194 not available
Expression system: Not provided

Quick links

Citations

39 review citations

Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants.
Degenhardt et al. (2009)
38 more

11 mentions without citation

Terpenoid synthase structures: a so far incomplete view of complex catalysis.
Gao et al. (2012)
10 more