1fot Summary



The structure was published by Mashhoon, N., Carmel, G., Pflugrath, J.W., and Kuret, J., in 2001 in a paper entitled "Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of CAMP-DEPENDENT PROTEIN KINASE TYPE 1. This molecule has the UniProt identifier P06244 (KAPA_YEAST)search. The sample contained 318 residues which is < 90% of the natural sequence. Out of 318 residues 299 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CAMP-DEPENDENT PROTEIN KINASE TYPE 1 P06244 (81-397) (KAPA_YEAST)search Saccharomyces cerevisiae S288csearch < 90% 318 94%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06244 (81 - 397) CAMP-DEPENDENT PROTEIN KINASE TYPE 1 Saccharomyces cerevisiae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Protein kinases, catalytic subunitsearch Transferase(Phosphotransferase) domain 1search, Phosphorylase Kinase; domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P06244) transferase activity, transferring phosphorus-containing groupssearch protein kinase activitysearch protein serine/threonine kinase activitysearch ATP bindingsearch protein phosphorylationsearch

Chain InterPro annotation
A Protein kinase domainsearch AGC-kinase, C-terminalsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch