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EBI PDBe PDBeView

PDBe Entry: 1fih view

N-ACETYLGALACTOSAMINE BINDING MUTANT OF MANNOSE-BINDING PROTEIN A (QPDWG-HDRPY), COMPLEX WITH N-ACETYLGALACTOSAMINE
Summary
Header SUGAR BINDING PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.95 Å, R-factor: 23.7%, Free R-factor: 26.9%, Spacegroup: C 1 2 1
Released 23/08/2000, deposition: 03/08/2000, last revision: 24/02/2009
Authors Feinberg, H.search; Torgerson, D.search; Drickamer, K.search; Weis, W.I.search
Primary citation Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.BIOL.CHEM.search vol:275, pag:35176-35184 (2000) [PubMed ID 10931846 ]search
Keywords lectinsearch, C-type lectinsearch, calcium-binding proteinsearch, SUGAR BINDING PROTEINsearch
Organism Rattus norvegicus(Norway rat) 10116search(A B C)
UniProt Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) P19999search (A B C)
Solvent A, B, C
Related entries 1fif
Polymers
Id Name Type UniProt Residues Observed
A, B, C MANNOSE-BINDING PROTEIN A Protein P19999 (MBL1_RAT)search
 154 100%
Heterogens
Id Name Ligands
A, B, C N-ACETYL-D-GALACTOSAMINE NGA search
A, B, C CALCIUM ION CA search
A, B, C CHLORIDE ION CL search
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