1fgv

X-ray diffraction
1.9Å resolution

X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213000 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H52 FV (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 109 amino acids
Theoretical weight: 11.91 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins
H52 FV (HEAVY CHAIN) Chain: H
Molecule details ›
Chain: H
Length: 124 amino acids
Theoretical weight: 13.69 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 64.2Å b: 61.3Å c: 51.8Å
α: 90° β: 99° γ: 90°
R-values:
R R work R free
0.18 0.18 not available
Expression system: Not provided