› 1fel

X-ray diffraction
1.8Å resolution

CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN

Released:
DOI: 10.2210/pdb1fel/pdb
PDB entry 1fel coloured by chain, front view.
PDB entry 1fel coloured by chain, side view.
PDB entry 1fel coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
Zanotti G, Marcello M, Malpeli G, Folli C, Sartori G, Berni R
J Biol Chem 269 29613-20 (1994)
PMID: 7961949

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148473 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 4 Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 21.1 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P18902 (Residues: 1-183; Coverage: 100%)
Gene name: RBP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand FEN 1 x FEN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 46.63Å b: 49.26Å c: 76.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 not available not available
Expression system: Not provided

Quick links

Citations

3 review citations

The transthyretin-retinol-binding protein complex.
Monaco HL. (2000)
2 more

4 mentions without citation

Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease.
Cioffi et al. (2014)
3 more