1fcu Summary



The structure was published by Markovic-Housley, Z., Miglierini, G., Soldatova, L., Rizkallah, P.J., Muller, U., and Schirmer, T., in 2000 in a paper entitled "Crystal structure of hyaluronidase, a major allergen of bee venom." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of HYALURONOGLUCOSAMINIDASE. This molecule has the UniProt identifier Q08169 (HUGA_APIME)search. The sample contained 350 residues which is 99% of the natural sequence. Out of 350 residues 324 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HYALURONOGLUCOSAMINIDASE Q08169 (33-382) (HUGA_APIME)search Apis melliferasearch 99% 350 92%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q08169 (33 - 382) HYALURONOGLUCOSAMINIDASE Apis mellifera

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q08169) Bee venom hyaluronidasesearch Aldolase class Isearch PF01630: Hyaluronidasesearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A (Q08169) extracellular regionsearch metabolic processsearch defense responsesearch carbohydrate metabolic processsearch hydrolase activity, acting on glycosyl bondssearch hyalurononglucosaminidase activitysearch catalytic activitysearch hydrolase activitysearch

Chain InterPro annotation
A Glycoside hydrolase family 56, bee venom hyaluronidasesearch Aldolase-type TIM barrelsearch Glycoside hydrolase superfamilysearch Hyaluronidasesearch