1fc2

X-ray diffraction
2.8Å resolution

Crystallographic Refinement and Atomic Models of a Human FC Fragment and its Complex with Fragment B of Protein A from Staphylococcus Aureus at 2.9-and 2.8-Angstroms Resolution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-134861 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin G-binding protein A Chain: C
Molecule details ›
Chain: C
Length: 58 amino acids
Theoretical weight: 6.61 KDa
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Expression system: Not provided
UniProt:
  • Canonical: P38507 (Residues: 212-269; Coverage: 12%)
Gene name: spa
Sequence domains: B domain
Structure domains: Immunoglobulin FC, subunit C
Immunoglobulin heavy constant gamma 1 Chain: D
Molecule details ›
Chain: D
Length: 224 amino acids
Theoretical weight: 25.24 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01857 (Residues: 106-328; Coverage: 56%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN, GAL, FUC
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 70.6Å b: 70.6Å c: 147.4Å
α: 90° β: 90° γ: 120°
Expression system: Not provided