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EBI PDBe PDBeView

PDBe Entry: 1fao view

STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Summary
Header SIGNALING PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 21.9%, Free R-factor: 23.2%, Spacegroup: P 21 21 21
Released 20/07/2000, deposition: 13/07/2000, last revision: 24/02/2009
Authors Ferguson, K.M.search; Kavran, J.M.search; Sankaran, V.G.search; Fournier, E.search; Isakoff, S.J.search; Skolnik, E.Y.search; Lemmon, M.A.search
Primary citation Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
MOL.CELLsearch vol:6, pag:373-384 (2000) [PubMed ID 10983984 ]search
Keywords PLECKSTRINsearch, 3-PHOSPHOINOSITIDESsearch, INOSITOL TETRAKISPHOSPHATE SIGNAL TRANSDUCTION PROTEINsearch, ADAPTOR PROTEINsearch, SIGNALING PROTEINsearch
Organism Homo sapiens(human) 9606search(A)
UniProt Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B-cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32) Q9UN19search (A)
Solvent A
Related entries 1fb8
Polymers
Id Name Type UniProt Residues Observed
A DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES Protein Q9UN19 (DAPP1_HUMAN)search
 126 79%
Heterogens
Id Name Ligands
A INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 4IP search
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