1f7u Summary

pdbe.org/1f7u
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CRYSTAL STRUCTURE OF THE ARGINYL-TRNA SYNTHETASE COMPLEXED WITH THE TRNA(ARG) AND L-ARG

The structure was published by Delagoutte, B., Moras, D., and Cavarelli, J., in 2000 in a paper entitled "tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely TRNA(ARG) and ARGINYL-TRNA SYNTHETASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ARGINYL-TRNA SYNTHETASE Q05506 (1-607) (SYRC_YEAST)search Saccharomyces cerevisiae S288csearch 100% 607 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q05506 (1 - 607) ARGINYL-TRNA SYNTHETASE Saccharomyces cerevisiae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q05506) Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetasessearch, Class I aminoacyl-tRNA synthetases (RS), catalytic domainsearch, Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domainsearch HUPssearch, Isoleucyl-tRNA Synthetase; Domain 1search, Gyrase A; domain 2search PF00750: tRNA synthetases class I (R)search, PF03485: Arginyl tRNA synthetase N terminal domainsearch, PF05746: DALR anticodon binding domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (Q05506) arginine-tRNA ligase activitysearch nucleotide bindingsearch ATP bindingsearch aminoacyl-tRNA ligase activitysearch ligase activitysearch cytoplasmsearch tRNA aminoacylation for protein translationsearch translationsearch arginyl-tRNA aminoacylationsearch

Chain InterPro annotation
A Arginine-tRNA ligasesearch Aminoacyl-tRNA synthetase, class I, conserved sitesearch Arginyl tRNA synthetase N-terminal domainsearch DALR anticodon bindingsearch Aminoacyl-tRNA synthetase, class 1a, anticodon-bindingsearch Rossmann-like alpha/beta/alpha sandwich foldsearch