1f7l Summary

pdbe.org/1f7l
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HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH COENZYME A AT 1.5A

The structure was published by Parris, K.D., Lin, L., Tam, A., et al., Fritz, C.C., Seehra, J., and Somers, W.S., in 2000 in a paper entitled "Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2000.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of HOLO-(ACYL CARRIER PROTEIN) SYNTHASE. This molecule has the UniProt identifier P96618 (ACPS_BACSU)search. The sample contained 121 residues which is 100% of the natural sequence. Out of 121 residues 116 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HOLO-(ACYL CARRIER PROTEIN) SYNTHASE P96618 (1-121) (ACPS_BACSU)search Bacillus subtilis subsp. subtilis str. 168search 99% 121 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P96618 (1 - 121) HOLO-(ACYL CARRIER PROTEIN) SYNTHASE Bacillus subtilis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P96618) Holo-(acyl carrier protein) synthase ACPSsearch 4'-phosphopantetheinyl transferasesearch PF01648: 4'-phosphopantetheinyl transferase superfamilysearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P96618) magnesium ion bindingsearch holo-[acyl-carrier-protein] synthase activitysearch metal ion bindingsearch transferase activitysearch macromolecule biosynthetic processsearch fatty acid biosynthetic processsearch fatty acid metabolic processsearch lipid metabolic processsearch cytoplasmsearch

Chain InterPro annotation
A Holo-[acyl carrier protein] synthasesearch Phosphopantethiene-protein transferase domainsearch 4'-phosphopantetheinyl transferase superfamilysearch