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EBI PDBe PDBeView

PDBe Entry: 1f40 view

SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A NEUROTROPHIC LIGAND
Summary
Header ISOMERASEsearch
Method SOLUTION NMR
Experiment Spacegroup: P 1
Released 08/11/2000, deposition: 07/06/2000, last revision: 24/02/2009
Authors Sich, C.search; Improta, S.search; Cowley, D.J.search; Guenet, C.search; Merly, J.P.search; Teufel, M.search; Saudek, V.search
Primary citation Solution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamics.
EUR.J.BIOCHEM.search vol:267, pag:5342-5354 (2000) [PubMed ID 10951192 ]search
Keywords isomerasesearch
EC 5.2.1.8 ExPASy BRENDA search (A)
Organism Homo sapiens(human) 9606search(A)
UniProt FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Immunophilin FKBP12) (12 kDa FKBP) (FKBP-12) P62942search (A)
Related entries 1fkj, 1fkg
Polymers
Id Name Type UniProt Residues Observed
A FK506 BINDING PROTEIN (FKBP12) Protein P62942 (FKB1A_HUMAN)search
 107 100%
Heterogens
Id Name Ligands
A (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE GPI search
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