1f2i Summary

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COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA

The structure was published by Wang, B.S., Grant, R.A., and Pabo, C.O., in 2001 in a paper entitled "Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.35 Å and deposited in 2000.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely 5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3' and FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
G FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%
H FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%
I FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%
J FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%
K FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%
L FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 P08046 (331-389) (EGR1_MOUSE)search Mus musculussearch < 90% 73 90%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08046 (331 - 389) FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12 Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
G, H, I, J, K, L Classic zinc finger, C2H2search Classic Zinc Fingersearch Zinc-finger double domainsearch

Chain ID Molecular function (GO)
G, H, I, J, K, L (P08046) metal ion bindingsearch nucleic acid bindingsearch

Chain InterPro annotation
G, H, I, J, K, L Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch