1exn Summary

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T5 5'-EXONUCLEASE

The structure was published by Ceska, T.A., Sayers, J.R., Stier, G., and Suck, D., in 1996 in a paper entitled "A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of 5'-EXONUCLEASE.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 5'-EXONUCLEASE P06229 (2-291) (EXO5_BPT5)search Enterobacteria phage T5search 100% 290 93%
B 5'-EXONUCLEASE P06229 (2-291) (EXO5_BPT5)search Enterobacteria phage T5search 100% 290 93%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06229 (2 - 291) 5'-EXONUCLEASE Enterobacteria phage T5

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P06229) 5' to 3' exonuclease, C-terminal subdomainsearch, 5' to 3' exonuclease catalytic domainsearch 5' to 3' exonuclease, C-terminal subdomainsearch, 5'-nucleasesearch PF01367: 5'-3' exonuclease, C-terminal SAM foldsearch, PF02739: 5'-3' exonuclease, N-terminal resolvase-like domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (P06229) catalytic activitysearch metal ion bindingsearch DNA bindingsearch hydrolase activitysearch endonuclease activitysearch nuclease activitysearch exonuclease activitysearch metabolic processsearch nucleic acid phosphodiester bond hydrolysissearch

Chain InterPro annotation
A, B 5'-3' exonuclease, N-terminalsearch Helix-hairpin-helix motif, class 2search 5'-3' exonuclease, C-terminal domainsearch 5'-3' exonuclease, alpha-helical arch, N-terminalsearch PIN domain-likesearch