› › Function and Biology

SIALIDASE COMPLEXED WITH 2-DEOXY-2,3-DEHYDRO-N-ACETYLNEURAMINIC ACID

Source organism: Micromonospora viridifaciens
Biochemical function: exo-alpha-sialidase activity
Biological process: not assigned
Cellular component: not assigned

Quick links

EC 3.2.1.18: Exo-alpha-sialidase

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
Systematic name:
Acetylneuraminyl hydrolase
Alternative Name(s):
  • Acetylneuraminidase
  • Alpha-neuraminidase
  • N-acylneuraminate glycohydrolase
  • Neuraminidase
  • Sialidase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF13088
Domain description: BNR repeat-like domain
Occurring in:
  1. Sialidase
The deposited structure of PDB entry 1eus contains 1 copy of Pfam domain PF13088 (BNR repeat-like domain) in Sialidase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR011040
Domain description: Sialidase
Occurring in:
  1. Sialidase
IPR026856
Domain description: Sialidase family
Occurring in:
  1. Sialidase
IPR036278
Domain description: Sialidase superfamily
Occurring in:
  1. Sialidase

Structure domain

CATH CATH domain
2.120.10.10
Class: Mainly Beta
Architecture: 6 Propeller
Topology: Neuraminidase
Homology: Neuraminidase
Occurring in:
  1. Sialidase
The deposited structure of PDB entry 1eus contains 1 copy of CATH domain 2.120.10.10 (Neuraminidase) in Sialidase. Showing 1 copy in chain A.
SCOP SCOP annotation
50940
Class: All beta proteins
Fold: 6-bladed beta-propeller
Superfamily: Sialidases
Occurring in:
  1. Sialidase
The deposited structure of PDB entry 1eus contains 1 copy of SCOP domain 50940 (Sialidases (neuraminidases)) in Sialidase. Showing 1 copy in chain A.

Quick links