1eq2 Summary

pdbe.org/1eq2
spacer

THE CRYSTAL STRUCTURE OF ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE

The structure was published by Deacon, A.M., Ni, Y.S., Coleman Jr., W.G., and Ealick, S.E., in 2000 in a paper entitled "The crystal structure of ADP-L-glycero-D-mannoheptose 6-epimerase: catalysis with a twist." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2000.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
B ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
C ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
D ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
E ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
F ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
G ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
H ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
I ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%
J ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE P67910 (1-310) (HLDD_ECOLI)search Escherichia coli K-12search 100% 310 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P67910 (1 - 310) ADP-L-GLYCERO-D-MANNOHEPTOSE 6-EPIMERASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F, G, H, I, J (P67910) Tyrosine-dependent oxidoreductasessearch NAD(P)-binding Rossmann-like Domainsearch, UDP-galactose 4-epimerase, domain 1search PF01370: NAD dependent epimerase/dehydratase familysearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D, E, F, G, H, I, J (P67910) ADP-glyceromanno-heptose 6-epimerase activitysearch coenzyme bindingsearch NADP bindingsearch catalytic activitysearch NADP+ bindingsearch protein bindingsearch isomerase activitysearch carbohydrate metabolic processsearch lipopolysaccharide core region biosynthetic processsearch ADP-L-glycero-beta-D-manno-heptose biosynthetic processsearch lipopolysaccharide biosynthetic processsearch response to stresssearch cytosolsearch membranesearch

Chain InterPro annotation
A, B, C, D, E, F, G, H, I, J NAD-dependent epimerase/dehydratase, N-terminal domainsearch ADP-L-glycero-D-manno-heptose-6-epimerasesearch NAD(P)-binding domainsearch