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EBI PDBe PDBeView

PDBe Entry: 1enu view

A new target for shigellosis: Rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.95 Å, R-factor: 17.6%, Free R-factor: 21.1%, Spacegroup: C 1 2 1
Released 19/04/2000, deposition: 21/03/2000, last revision: 24/02/2009
Authors Gradler, U.search; Gerber, H.D.search; Goodenough-Lashua, D.M.search; Garcia, G.A.search; Ficner, R.search; Reuter, K.search; Stubbs, M.T.search; Klebe, G.search
Primary citation A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase.
J.MOL.BIOL.search vol:306, pag:455-467 (2001) [PubMed ID 11178905 ]search
Keywords TRNA-MODIFYING ENZYMEsearch, GLYCOSYLTRANSFERASEsearch
EC 2.4.2.29 ExPASy BRENDA search (A)
Organism Zymomonas mobilis 542search(A)
UniProt Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (tRNA-guanine transglycosylase) (Guanine insertion enzyme) P28720search (A)
Solvent A
Related entries 1efz, 1pud
Polymers
Id Name Type UniProt Residues Observed
A TRNA-GUANINE TRANSGLYCOSYLASE Protein P28720 (TGT_ZYMMO)search
 386 96%
Heterogens
Id Name Ligands
A ZINC ION ZN search
A 4-AMINOPHTHALHYDRAZIDE APZ search
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