1elz Summary

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E. COLI ALKALINE PHOSPHATASE MUTANT (S102G)

The structure was published by Stec, B., Hehir, M.J., Brennan, C., Nolte, M., and Kantrowitz, E.R., in 1998 in a paper entitled "Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of ALKALINE PHOSPHATASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ALKALINE PHOSPHATASE P00634 (23-471) (PPB_ECOLI)search Escherichia coli K-12search 99% 449 100%
B ALKALINE PHOSPHATASE P00634 (23-471) (PPB_ECOLI)search Escherichia coli K-12search 99% 449 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00634 (23 - 471) ALKALINE PHOSPHATASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P00634) Alkaline phosphatasesearch Alkaline Phosphatase, subunit Asearch PF00245: Alkaline phosphatasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P00634) catalytic activitysearch metal ion bindingsearch alkaline phosphatase activitysearch hydrogenase (acceptor) activitysearch zinc ion bindingsearch hydrolase activitysearch protein bindingsearch oxidoreductase activity, acting on phosphorus or arsenic in donorssearch magnesium ion bindingsearch phosphatase activitysearch dephosphorylationsearch oxidation-reduction processsearch metabolic processsearch periplasmic spacesearch outer membrane-bounded periplasmic spacesearch

Chain InterPro annotation
A, B Alkaline phosphatasesearch Alkaline phosphatase-like, alpha/beta/alphasearch Alkaline-phosphatase-like, core domainsearch