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EBI PDBe PDBeView

PDBe Entry: 1elr view

Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
Summary
Header CHAPERONEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.9 Å, R-factor: 18.1%, Free R-factor: 21.9%, Spacegroup: C 1 2 1
Released 26/04/2000, deposition: 14/03/2000, last revision: 24/02/2009
Authors Scheufler, C.search; Brinker, A.search; Hartl, F.U.search; Moarefi, I.search
Primary citation Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
CELL(CAMBRIDGE,MASS.)search vol:101, pag:199-210 (2000) [PubMed ID 10786835 ]search
Keywords Hopsearch, Tpr-Domainsearch, Peptide-Complexsearch, Helical Repeatsearch, Hsp90search, Protein Bindingsearch, CHAPERONEsearch
Organism Homo sapiens(human) 9606search(A)
UniProt Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY-REN-11 antigen) P31948search (A)
Solvent A, B
Related entries 1elw
Polymers
Id Name Type UniProt Residues Observed
A TPR2A-DOMAIN OF HOP Protein P31948 (STIP1_HUMAN)search
 131 97%
B HSP90-PEPTIDE MEEVD Mixed
6 100%
Heterogens
Id Name Ligands
A NICKEL (II) ION NI search
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