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EBI PDBe PDBeView

PDBe Entry: 1ege view

STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Summary
Header ELECTRON TRANSFERsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.75 Å, R-factor: 22.1%, Spacegroup: P 43 21 2
Released 16/06/1997, deposition: 11/04/1996, last revision: 24/02/2009
Authors Lee, H.J.search; Wang, M.search; Paschke, R.search; Nandy, A.search; Ghisla, S.search; Kim, J.P.search
Primary citation Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
BIOCHEMISTRYsearch vol:35, pag:12412-12420 (1996) [PubMed ID 8823176 ]search
Keywords ACYL-COA DEHYDROGENASEsearch, FLAVOPROTEINsearch, ELECTRON TRANSFERsearch
EC 1.3.99.3 ExPASy BRENDA search (A B C D)
Organism Homo sapiens(human) 9606search(A B C D)
UniProt Medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.3) (MCAD) P11310search (A B C D)
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D MEDIUM CHAIN ACYL-COA DEHYDROGENASE Protein P11310 (ACADM_HUMAN)search
 396 97%
Heterogens
Id Name Ligands
A, B, C, D FLAVIN-ADENINE DINUCLEOTIDE FAD search
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