spacer HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
CATH: Protein Structure Classification
CATH code 2.30.30.40 search
Domains
1efnA00 , 1efnC00
Name Fyn tyrosine kinase. Chain: a, c. Fragment: sh3 domain, residues 85-141. Synonym: src-homology 3 domain. Engineered: yes. Mutation: yes. Hiv-1 nef protein. Chain: b, d. Fragment: conserved core domain of nef, residues 71-203. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hiv-1 nef. Expressedin: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers A, C
Hierarchy
Class Mainly Betasearch
Architecture Roll search
Topology SH3 type barrels. search
Homologous superfamily SH3 Domains search
 
CATH code 3.30.62.10 search
Domains
1efnB00 , 1efnD00
Name Fyn tyrosine kinase. Chain: a, c. Fragment: sh3 domain, residues 85-141. Synonym: src-homology 3 domain. Engineered: yes. Mutation: yes. Hiv-1 nef protein. Chain: b, d. Fragment: conserved core domain of nef, residues 71-203. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hiv-1 nef. Expressedin: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers B, D
Hierarchy
Class Alpha Betasearch
Architecture 2-Layer Sandwich search
Topology Nef Regulatory Factor search
Homologous superfamily Nef Regulatory Factor search
 
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