1edn Summary

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HUMAN ENDOTHELIN-1

The structure was published by Janes, R.W., Peapus, D.H., and Wallace, B.A., in 1994 in a paper entitled "The crystal structure of human endothelin." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.18 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of ENDOTHELIN-1. This molecule has the UniProt identifier P05305 (EDN1_HUMAN)search. The sample contained 21 residues which is < 90% of the natural sequence. Out of 21 residues 21 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ENDOTHELIN-1 P05305 (53-73) (EDN1_HUMAN)search Homo sapienssearch < 90% 21 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05305 (53 - 73) ENDOTHELIN-1 Homo sapiens

Chain Structural classification (SCOP) Sequence family (Pfam)
A Endothelin-likesearch Endothelin familysearch

Chain ID Biological process (GO) Cellular component (GO)
A (P05305) regulation of vasoconstrictionsearch extracellular regionsearch

Chain InterPro annotation
A Endothelin-like toxinsearch Endothelin-like toxin, conserved sitesearch