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PDBe Entry: 1ecv 
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 5-IODO-2-(OXALYL-AMINO)-BENZOIC ACID
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 1.95 Å, R-factor: 19.4%, Free R-factor: 24.9%, Spacegroup: P 31 2 1
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15/03/2000, deposition: 26/01/2000, last revision: 24/02/2009
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Andersen, H.S.; Iversen, L.F.; Branner, S.; Rasmussen, H.B.; Moller, N.P.H.
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2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases.
J.BIOL.CHEM. vol:275, pag:7101-7108 (2000) [PubMed ID 10702277 ]
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HYDROLASE, PHOSPHORYLATION, LIGAND, INHIBITOR
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3.1.3.48 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) P18031 (A)
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A
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1c83, 1c84, 1c85, 1c86, 1c87, 1c88
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| A |
PROTEIN-TYROSINE PHOSPHATASE 1B |
Protein |
P18031 (PTN1_HUMAN)
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298 |
99% |
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| A |
ACETATE ION |
ACT
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| A |
5-IODO-2-(OXALYL-AMINO)-BENZOIC ACID |
878
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