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EBI PDBe PDBeView

PDBe Entry: 1ec6 view

CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN
Summary
Header RNA BINDING PROTEIN/RNAsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.4 Å, R-factor: 22.4%, Free R-factor: 29.1%, Spacegroup: P 21 21 21
Released 21/02/2000, deposition: 25/01/2000, last revision: 24/02/2009
Authors Lewis, H.A.search; Musunuru, K.search; Jensen, K.B.search; Edo, C.search; Chen, H.search
Primary citation Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
CELL(CAMBRIDGE,MASS.)search vol:100, pag:323-332 (2000) [PubMed ID 10676814 ]search
Keywords KH domainsearch, alpha-beta foldsearch, RNA-binding motifsearch, protein/RNA structuresearch, RNA BINDING PROTEIN/RNA COMPLEXsearch
Organism Homo sapiens(human) 9606search(A B)
UniProt RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein) Q9UNW9search (A B)
Solvent A, B, C, D
Polymers
Id Name Type UniProt Residues Observed
C, D 20-MER RNA HAIRPIN RNA
20 100%
A, B RNA-BINDING PROTEIN NOVA-2 Protein Q9UNW9 (NOVA2_HUMAN)search
 87 100%
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