PDBe Entry: 1ebd

DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE

Summary

Header

COMPLEX (OXIDOREDUCTASE/TRANSFERASE)

Method

X-RAY DIFFRACTION

Experiment

Resolution: 2.6 Å, R-factor: 21.5%, Spacegroup: P 31 2 1

Released

11/07/1996, deposition: 03/02/1996, last revision: 24/02/2009

Authors

Mande, S.S.

; Sarfaty, S.

; Allen, M.D.

; Perham, R.N.

; Hol, W.G.J.

Primary citation

Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase.
STRUCTURE

vol:4, pag:277-286 (1996) [PubMed ID 8805537 ]

Keywords

REDOX-ACTIVE CENTER

, GLYCOLYSIS

, OXIDOREDUCTASE

, COMPLEX (OXIDOREDUCTASE/TRANSFERASE) COMPLEX

1.8.1.4 ExPASy BRENDA

(A B), 2.3.1.12 ExPASy BRENDA

(C)

Organism

Geobacillus stearothermophilus 1422

(A B C)

UniProt

Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate complex) P11959

(A B)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (E2) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) P11961

(C)

Solvent

A, B

Polymers

Id	Name	Type	UniProt	Residues	Observed
A, B	DIHYDROLIPOAMIDE DEHYDROGENASE	Protein	P11959 (DLDH1_BACST)	455	100%
C	DIHYDROLIPOAMIDE ACETYLTRANSFERASE	Protein	P11961 (ODP2_BACST)	41	100%

Heterogens

Id	Name	Ligands
A, B	FLAVIN-ADENINE DINUCLEOTIDE	FAD