STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE
The structure was published by Walker, E.H., Pacold, M.E., Perisic, O., et al., Hawkins, P.T., Whymann, M.P., and Williams, R.L., in 2000 in a paper entitled "Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2000.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT. This molecule has the UniProt identifier P48736 (PK3CG_HUMAN). The sample contained 966 residues which is < 90% of the natural sequence. Out of 966 residues 838 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: