PDB entry 1e8x (supersedes 1qmm)
STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING
The structure was published by Walker, E.H., Pacold, M.E., Perisic, O., et al., Hawkins, P.T., Whymann, M.P., and Williams, R.L., in 2000 in a paper entitled "Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2000.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT. This molecule has the UniProt identifier O02697 (PK3CG_PIG). The sample contained 961 residues which is < 90% of the natural sequence. Out of 961 residues 841 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: