› › Structure analysis

Structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase

X-ray diffraction
2.5Å resolution
PDB entry 1e8t coloured by chain, front view.
PDB entry 1e8t coloured by chain, side view.
PDB entry 1e8t coloured by chain, top view.
Source organism: Newcastle disease virus (strain Kansas)
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Hemagglutinin-neuraminidase
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 32994.5 Å2
Buried surface area: 3254.8 Å2
Dissociation area: 739.21 Å2
Dissociation energy (ΔGdiss): -3.13 kcal/mol
Dissociation entropy (TΔSdiss): 14.07 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-192971

Macromolecules

Hemagglutinin-neuraminidase
Chains: A, B
Length: 454 amino acids
Theoretical weight: 49.86 KDa
Source organism: Newcastle disease virus (strain Kansas)
UniProt:
  • Canonical: Q9Q2W5 (Residues: 124-577; Coverage: 79%)
Gene name: HN
Pfam: Haemagglutinin-neuraminidase
InterPro:
CATH: Neuraminidase
SCOP: Sialidases (neuraminidases)
Hemagglutinin-neuraminidase in PDB entry 1e8t, assembly 1, front view.
Hemagglutinin-neuraminidase in PDB entry 1e8t, assembly 1, side view.
Hemagglutinin-neuraminidase in PDB entry 1e8t, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links