 |
PDBe Entry: 1e33 
CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT P426L
 |
HYDROLASE
|
|
X-RAY DIFFRACTION
|
|
Resolution: 2.5 Å, R-factor: 18.7%, Free R-factor: 25.0%, Spacegroup: I 4 2 2
|
|
25/05/2001, deposition: 06/06/2000, last revision: 16/06/2009
|
|
Von Buelow, R.; Schmidt, B.; Dierks, T.; Von Figura, K.; Uson, I.
|
Defective Oligomerization of Arylsulfatase a as a Cause of its Instability in Lysosomes and Metachromatic Leukodystrophy.
J.BIOL.CHEM. vol:277, pag:9455-9461 (2002) [PubMed ID 11777924 ]
|
|
HYDROLASE, CEREBROSIDE-3-SULFATE HYDROLYSIS, LYSOSOMAL ENZYME, FORMYLGLYCINE
|
|
3.1.6.8 ExPASy BRENDA (P)
|
|
Homo sapiens(human) 9606(P)
|
|
Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C] P15289 (P)
|
|
P
|
|
1auk, 1e3c, 1e2s
|
| P |
ARYLSULFATASE A |
Protein |
P15289 (ARSA_HUMAN)
|
489 |
98% |
|
| P |
SUGAR (2-MER) |
NDG
|
| P |
MAGNESIUM ION |
MG
|
|
|
