1e07 Summary


Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data

The structure was published by Boehm, M.K. and Perkins, S.J., in 2000 in a paper entitled "Structural Models for Carcinoembryonic Antigen and its Complex with the Single-Chain Fv Antibody Molecule Mfe23." (abstract).

The structure was determined using Solution scattering and deposited in 2000.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of CARCINOEMBRYONIC ANTIGEN. This molecule has the UniProt identifier P06731 (CEAM5_HUMAN)search. The sample contained 642 residues which is 96% of the natural sequence. Out of 642 residues 88 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CARCINOEMBRYONIC ANTIGEN P06731 (35-676) (CEAM5_HUMAN)search Homo sapienssearch 96% 642 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06731 (35 - 676) CARCINOEMBRYONIC ANTIGEN Homo sapiens

Chain Sequence family (Pfam)
A (P06731) PF07679: Immunoglobulin I-set domainsearch, PF07686: Immunoglobulin V-set domainsearch, PF13895: Immunoglobulin domainsearch, PF13927: Immunoglobulin domainsearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A (P06731) anchored component of membranesearch membranesearch extracellular exosomesearch plasma membranesearch integral component of external side of plasma membranesearch basolateral plasma membranesearch integral component of plasma membranesearch negative regulation of myotube differentiationsearch negative regulation of apoptotic processsearch homotypic cell-cell adhesionsearch negative regulation of anoikissearch identical protein bindingsearch protein homodimerization activitysearch GPI anchor bindingsearch

Chain InterPro annotation
A Immunoglobulin subtype 2search Immunoglobulin subtypesearch Immunoglobulin-like domainsearch Immunoglobulin I-setsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch