1dug Summary

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STRUCTURE OF THE FIBRINOGEN G CHAIN INTEGRIN BINDING AND FACTOR XIIIA CROSSLINKING SITES OBTAINED THROUGH CARRIER PROTEIN DRIVEN CRYSTALLIZATION

The structure was published by Ware, S., Donahue, J.P., Hawiger, J., and Anderson, W.F., in 1999 in a paper entitled "Structure of the fibrinogen gamma-chain integrin binding and factor XIIIa cross-linking sites obtained through carrier protein driven crystallization." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of chimera of GLUTATHIONE S-TRANSFERASE-synthetic LINKEr-C-TERMINAL FIBRINOGEN GAMMA CHAIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A chimera of GLUTATHIONE S-TRANSFERASE-synthetic LINKEr-C-TERMINAL FIBRINOGEN GAMMA CHAIN P02679 (424-433) (FIBG_HUMAN)search ,
P08515 (2-218) (GST26_SCHJA)search
Homo sapienssearch ,
Schistosoma japonicumsearch
95% ,
98%
234 100%
B chimera of GLUTATHIONE S-TRANSFERASE-synthetic LINKEr-C-TERMINAL FIBRINOGEN GAMMA CHAIN P02679 (424-433) (FIBG_HUMAN)search ,
P08515 (2-218) (GST26_SCHJA)search
Homo sapienssearch ,
Schistosoma japonicumsearch
95% ,
98%
234 100%


Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P08515) Glutathione S-transferase (GST), C-terminal domainsearch, Glutathione S-transferase (GST), N-terminal domainsearch Glutaredoxinsearch, Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2search PF00043: Glutathione S-transferase, C-terminal domainsearch, PF02798: Glutathione S-transferase, N-terminal domainsearch
A, B (P02679)

Chain ID Molecular function (GO) Biological process (GO)
A, B (P08515P02679) glutathione transferase activitysearch transferase activitysearch metabolic processsearch

Chain InterPro annotation
A, B Glutathione S-transferase, N-terminalsearch Glutathione S-transferase, C-terminalsearch Glutathione S-transferase, C-terminal-likesearch Thioredoxin-like foldsearch