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EBI PDBe PDBeView

PDBe Entry: 1dqy view

CRYSTAL STRUCTURE OF ANTIGEN 85C FROM MYCOBACTERIUM TUBERCULOSIS WITH DIETHYL PHOSPHATE INHIBITOR
Summary
Header IMMUNE SYSTEMsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.83 Å, R-factor: 18.6%, Free R-factor: 18.87%, Spacegroup: C 1 2 1
Released 12/07/2000, deposition: 05/01/2000, last revision: 24/02/2009
Authors Ronning, D.R.search; Klabunde, T.search; Sacchettini, J.C.search; TB Structural Genomics Consortium (TBSGC)search
Primary citation Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines.
NAT.STRUCT.BIOL.search vol:7, pag:141-146 (2000) [PubMed ID 10655617 ]search
Keywords ANTIGENsearch, 85Csearch, MYCOBACTERIUM TUBERCULOSISsearch, FIBRONECTINsearch, DPIsearch, Structural Genomicssearch, PSIsearch, Protein Structure Initiativesearch, TB Structural Genomics Consortiumsearch, TBSGCsearch, IMMUNE SYSTEMsearch
Organism Mycobacterium tuberculosis 1773search(A)
UniProt Antigen 85-C precursor (Antigen 85 complex C) (Ag85C) (85C) (Mycolyl transferase 85C) (EC 2.3.1.-) (Fibronectin-binding protein C) P0A4V4search (A)
Solvent A
Related entries 1dqz
Polymers
Id Name Type UniProt Residues Observed
A PROTEIN (ANTIGEN 85-C) Protein P0A4V4 (A85C_MYCTU)search
 283 100%
Heterogens
Id Name Ligands
A DIETHYL PHOSPHONATE DEP search
A (4R)-2-METHYLPENTANE-2,4-DIOL MRD search
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