1dqr Summary

pdbe.org/1dqr
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CRYSTAL STRUCTURE OF RABBIT PHOSPHOGLUCOSE ISOMERASE, A GLYCOLYTIC ENZYME THAT MOONLIGHTS AS NEUROLEUKIN, AUTOCRINE MOTILITY FACTOR, AND DIFFERENTIATION MEDIATOR

The structure was published by Jeffery, C.J., Bahnson, B.J., Chien, W., Ringe, D., and Petsko, G.A., in 2000 in a paper entitled "Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PHOSPHOGLUCOSE ISOMERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PHOSPHOGLUCOSE ISOMERASE Q9N1E2 (2-558) (G6PI_RABIT)search Oryctolagus cuniculussearch 100% 557 99%
B PHOSPHOGLUCOSE ISOMERASE Q9N1E2 (2-558) (G6PI_RABIT)search Oryctolagus cuniculussearch 100% 557 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9N1E2 (2 - 558) PHOSPHOGLUCOSE ISOMERASE Oryctolagus cuniculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q9N1E2) Phosphoglucose isomerase, PGIsearch Glucose-6-phosphate isomerase like protein; domain 1search, Phosphoglucose isomerase, C-terminal domainsearch PF00342: Phosphoglucose isomerasesearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B (Q9N1E2) glucose-6-phosphate isomerase activitysearch isomerase activitysearch cytokine activitysearch extracellular regionsearch cytoplasmsearch extracellular spacesearch gluconeogenesissearch glycolytic processsearch angiogenesissearch

Chain InterPro annotation
A, B Phosphoglucose isomerase (PGI)search Phosphoglucose isomerase, conserved sitesearch Phosphoglucose isomerase, C-terminalsearch