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PDBe Entry: 1dqa 
COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG, COA, AND NADP+
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OXIDOREDUCTASE
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X-RAY DIFFRACTION
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Resolution: 2.0 Å, R-factor: 16.8%, Free R-factor: 19.7%, Spacegroup: P 1 21 1
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08/03/2000, deposition: 30/12/1999, last revision: 24/02/2009
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Istvan, E.S.; Palnitkar, M.; Buchanan, S.K.; Deisenhofer, J.
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Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J. vol:19, pag:819-830 (2000) [PubMed ID 10698924 ]
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OXIDOREDUCTASE, CHOLESTEROL BIOSYNTHESIS, HMG-COA, NADPH
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1.1.1.34 ExPASy BRENDA (A B C D)
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Homo sapiens(human) 9606(A B C D)
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase) P04035 (A B C D)
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A, B, C, D
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| A, B, C, D |
PROTEIN (HMG-COA REDUCTASE) |
Protein |
P04035 (HMDH_HUMAN)
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467 |
87% |
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| A, B, C, D |
COENZYME A |
COA
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| A, B, D, C |
3-HYDROXY-3-METHYL-GLUTARIC ACID |
MAH
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| A, B, C, D |
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE |
NAP
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