1dnk Summary

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THE X-RAY STRUCTURE OF THE DNASE I-D(GGTATACC)2 COMPLEX AT 2.3 ANGSTROMS RESOLUTION

The structure was published by Weston, S.A., Lahm, A., and Suck, D., in 1992 in a paper entitled "X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1992.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*GP*GP*TP*AP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*TP*AP*CP*C)-3'), and PROTEIN (DEOXYRIBONUCLEASE I (DNASE I) (E.C.3.1.21.1)).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (DEOXYRIBONUCLEASE I (DNASE I) (E.C.3.1.21.1)) P00639 (23-282) (DNAS1_BOVIN)search Bos taurussearch 100% 260 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00639 (23 - 282) PROTEIN (DEOXYRIBONUCLEASE I (DNASE I) (E.C.3.1.21.1)) Bos taurus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P00639) DNase I-likesearch Deoxyribonuclease I; Chain Asearch PF03372: Endonuclease/Exonuclease/phosphatase familysearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P00639) endodeoxyribonuclease activity, producing 5'-phosphomonoesterssearch endonuclease activitysearch deoxyribonuclease activitysearch hydrolase activitysearch nuclease activitysearch actin bindingsearch deoxyribonuclease I activitysearch nucleic acid phosphodiester bond hydrolysissearch DNA catabolic process, endonucleolyticsearch apoptotic processsearch DNA catabolic processsearch nuclear envelopesearch nucleussearch extracellular regionsearch

Chain InterPro annotation
A Endonuclease/exonuclease/phosphatasesearch Deoxyribonuclease Isearch Deoxyribonuclease I, active sitesearch