HUMAN CYCLIN-DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR HYMENIALDISINE
The structure was published by Meijer, L., Thunnissen, A.M., White, A.W., et al., Mandelkow, E.M., Kim, S.H., and Pettit, G.R., in 2000 in a paper entitled "Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1999.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of CYCLIN-DEPENDENT KINASE 2. This molecule has the UniProt identifier P24941 (CDK2_HUMAN). The sample contained 298 residues which is 100% of the natural sequence. Out of 298 residues 274 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: