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EBI PDBe PDBeView

PDBe Entry: 1dlj view

THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 17.9%, Free R-factor: 21.3%, Spacegroup: P 4 21 2
Released 31/05/2000, deposition: 09/12/1999, last revision: 24/02/2009
Authors Campbell, R.E.search; Mosimann, S.C.search; van de Rijn, I.search; Tanner, M.E.search; Strynadka, N.C.J.search
Primary citation The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation.
BIOCHEMISTRYsearch vol:39, pag:7012-7023 (2000) [PubMed ID 10841783 ]search
Keywords ROSSMANN FOLDsearch, TERNARY COMPLEXsearch, CRYSTALLOGRAPHIC DIMERsearch, OXIDOREDUCTASEsearch
EC 1.1.1.22 ExPASy BRENDA search (A)
Organism Streptococcus pyogenes 1314search(A)
UniProt UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) P0C0F4search (A)
Solvent A
Related entries 1dli
Polymers
Id Name Type UniProt Residues Observed
A UDP-GLUCOSE DEHYDROGENASE Protein P0C0F4 (UDG_STRPY)search
 402 100%
Heterogens
Id Name Ligands
A SULFATE ION SO4 search
A 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE NAI search
A URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID UGA search
A GLYCEROL GOL search
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