1dl6 Summary

pdbe.org/1dl6
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SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN

The structure was published by Chen, H.T., Legault, P., Glushka, J., Omichinski, J.G., and Scott, R.A., in 2000 in a paper entitled "Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1999.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of TRANSCRIPTION FACTOR II B (TFIIB). This molecule has the UniProt identifier Q00403 (TF2B_HUMAN)search. The sample contained 58 residues which is < 90% of the natural sequence. Out of 58 residues 58 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TRANSCRIPTION FACTOR II B (TFIIB) Q00403 (2-59) (TF2B_HUMAN)search Homo sapienssearch < 90% 58 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q00403 (2 - 59) TRANSCRIPTION FACTOR II B (TFIIB) Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Transcriptional factor domainsearch N-terminal domain of TfIIbsearch TFIIB zinc-bindingsearch

Chain ID Biological process (GO) Molecular function (GO)
A (Q00403) regulation of transcription, DNA-templatedsearch DNA-templated transcription, initiationsearch zinc ion bindingsearch

Chain InterPro annotation
A Transcription factor TFIIBsearch Zinc finger, TFIIB-typesearch