1dl5 Summary



The structure was published by Skinner, M.M., Puvathingal, J.M., Walter, R.L., and Friedman, A.M., in 2000 in a paper entitled "Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE Q56308 (1-317) (PIMT_THEMA)search Thermotoga maritima MSB8search 100% 317 100%
B PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE Q56308 (1-317) (PIMT_THEMA)search Thermotoga maritima MSB8search 100% 317 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q56308) Protein-L-isoaspartyl O-methyltransferasesearch, Protein-L-isoaspartyl O-methyltransferase, C-terminal domainsearch Vaccinia Virus protein VP39search, Protein-L-isoaspartyl O-methyltransferase, C-terminal domainsearch PF01135: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)search

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (Q56308) cellular protein modification processsearch methylationsearch protein repairsearch protein methylationsearch protein-L-isoaspartate (D-aspartate) O-methyltransferase activitysearch transferase activitysearch methyltransferase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B Protein-L-isoaspartate(D-aspartate) O-methyltransferasesearch Protein-L-isoaspartyl O-methyltransferase, C-terminalsearch S-adenosyl-L-methionine-dependent methyltransferasesearch