1de6 Summary

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L-RHAMNOSE ISOMERASE

The structure was published by Korndorfer, I.P., Fessner, W.D., and Matthews, B.W., in 2000 in a paper entitled "The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of L-RHAMNOSE ISOMERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A L-RHAMNOSE ISOMERASE P32170 (1-419) (RHAA_ECOLI)search Escherichia coli K-12search 100% 426 97%
B L-RHAMNOSE ISOMERASE P32170 (1-419) (RHAA_ECOLI)search Escherichia coli K-12search 100% 426 97%
C L-RHAMNOSE ISOMERASE P32170 (1-419) (RHAA_ECOLI)search Escherichia coli K-12search 100% 426 97%
D L-RHAMNOSE ISOMERASE P32170 (1-419) (RHAA_ECOLI)search Escherichia coli K-12search 100% 426 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P32170 (1 - 419) L-RHAMNOSE ISOMERASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D (P32170) L-rhamnose isomerasesearch Divalent-metal-dependent TIM barrel enzymessearch PF06134: L-rhamnose isomerase (RhaA)search

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D (P32170) manganese ion bindingsearch L-rhamnose isomerase activitysearch isomerase activitysearch metal ion bindingsearch identical protein bindingsearch L-lyxose metabolic processsearch rhamnose metabolic processsearch rhamnose catabolic processsearch cytoplasmsearch

Chain InterPro annotation
A, B, C, D Rhamnose isomerasesearch Xylose isomerase-like, TIM barrel domainsearch