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PDBe Entry: 1dcy 
CRYSTAL STRUCTURE OF HUMAN S-PLA2 IN COMPLEX WITH INDOLE 3 ACTIVE SITE INHIBITOR
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HYDROLASE/HYDROLASE INHIBITOR
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X-RAY DIFFRACTION
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Resolution: 2.7 Å, R-factor: 21.8%, Free R-factor: 26.9%, Spacegroup: P 61 2 2
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12/11/1999, deposition: 05/11/1999, last revision: 24/02/2009
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Chirgadze, N.Y.; Schevitz, R.W.; Wery, J.-P.
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Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2.
NAT.STRUCT.BIOL. vol:2, pag:458-465 (1995) [PubMed ID 7664108 ]
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S-PLA2; STRUCTURE-BASED DRUG DESIGN, HYDROLASE/HYDROLASE INHIBITOR
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3.1.1.4 ExPASy BRENDA (A)
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Homo sapiens(human) 9606(A)
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Phospholipase A2, membrane associated precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Group IIA phospholipase A2) (GIIC sPLA2) (Non-pancreatic secretory phospholipase A2) (NPS-PLA2) P14555 (A)
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A
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1db4, 1db5
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| A |
PHOSPHOLIPASE A2 |
Protein |
P14555 (PA2GA_HUMAN)
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124 |
100% |
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| A |
CALCIUM ION |
CA
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| A |
1-BENZYL-5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID |
I3N
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