› 1dc8

Solution NMR

STRUCTURE OF A TRANSIENTLY PHOSPHORYLATED "SWITCH" IN BACTERIAL SIGNAL TRANSDUCTION

Released:
DOI: 10.2210/pdb1dc8/pdb
PDB entry 1dc8 coloured by chain, front view.
PDB entry 1dc8 coloured by chain, side view.
PDB entry 1dc8 coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
Structure of a transiently phosphorylated switch in bacterial signal transduction.
Kern D, Volkman BF, Luginbühl P, Nohaile MJ, Kustu S, Wemmer DE
Nature 402 894-8
PMID: 10622255

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154447 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding transcriptional regulator NtrC Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.72 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P41789 (Residues: 1-124; Coverage: 26%)
Gene names: STM4005, glnG, ntrC
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PHD 1 x PHD

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

20 review citations

Two-component signal transduction.
Stock et al. (2000)
19 more

16 mentions without citation

Choreographing an enzyme's dance.
Villali et al. (2010)
15 more